Wound care hydrogel · Founded 2021

Wound dressings that keep working for 48 hours.

HydroHeal is a blended composite hydrogel made from natural polymers and reduced graphene oxide. It swells, stays blood-compatible and releases silver sulfadiazine steadily into the wound.

See the solutionView the results
87.9%drug released in 48 h
0.989R² for release model
pH 7maximum swelling
Dressing profile At a glance
Base polymersArabinoxylan + carrageenan
Natural
ReinforcementReduced graphene oxide
rGO
Cross-linkerTetraethyl orthosilicate
TEOS
Why it matters: Chronic and repeated wounds need dressings that fight infection without frequent changes.
The problem

Wounds need more than a cover

Skin wounds that recur need careful, sustained treatment.

Infection risk

Open wounds need antibacterial protection over days, not minutes.

Frequent changes

Dressings that release drug too fast must be replaced often.

Biocompatibility

Materials in contact with wounds must be safe for blood and tissue.

Our solution

A natural, drug-releasing hydrogel

HydroHeal blends natural polymers with graphene oxide to control swelling, wetting and release.

Release

Sustained antibacterial delivery

87.9%silver sulfadiazine in 48 h
  • Franz diffusion test
  • Steady release
  • Fewer dressing changes
Safety

Blood compatible

Allformulations hemocompatible
  • Tested for hemocompatibility
  • Natural polymers
  • Suits wound contact
Response

Swells where it counts

pH 7maximum swelling
  • Less swelling in basic pH
  • Controlled degradation
  • Optimised formula BCH-3
How it works

How HydroHeal works

How the HydroHeal dressing is made and tested.

  1. 1

    Blend

    Arabinoxylan, carrageenan and reduced graphene oxide are mixed.

    ARXCGrGO
  2. 2

    Cross-link

    TEOS links the blend into a stable hydrogel.

    TEOS
  3. 3

    Load

    The hydrogel carries silver sulfadiazine, a common burn and wound antibacterial.

    Silver sulfadiazine
  4. 4

    Test

    Swelling, degradation, blood compatibility and release are measured.

    FT-IRSEMFranz cell
Results

What the research showed

Laboratory results for the blended composite hydrogels.

87.9%drug released in 48 h
0.989R², Baker–Lonsdale model
pH 7peak swelling
BCH-3best formulation
Release kinetics models tested
ModelFit
Baker–LonsdaleBest fit (R² = 0.989)
Korsmeyer–PeppasTested
HiguchiTested
Hixson–CrowellTested
Zero and first orderTested

Source: Khan et al., Polymers 13(21), 3703 (2021). doi:10.3390/polym13213703

Who it's for

Who HydroHeal is for

For clinics and patients who manage wounds over time.

Wound care clinics

  • Sustained antibacterial release
  • Fewer dressing changes
  • Natural materials

Patients

  • Longer-lasting protection
  • Moist healing environment
  • Blood-compatible material

Medical device partners

  • Scalable polymer blend
  • Adaptable drug load
  • Strong lab data
Where we are

Where the evidence stands

HydroHeal has in vitro laboratory data.

In vitro only

Release and safety were tested in the lab, not in patients.

No clinical trials yet

Healing outcomes in people have not been studied.

Regulatory path

Dressing approval, sterility and shelf-life work are ahead.

The team

The team

Founded in 2021 by the research team behind the study.

RA

Rashid Amin

Co-author of the HydroHeal research.

MK

Muhammad Umar Aslam Khan

Co-author of the HydroHeal research.

SR

Saiful Izwan Abd Razaq

Co-author of the HydroHeal research.

HM

Hassan Mehboob

Co-author of the HydroHeal research.

SR

Sarish Rehman

Co-author of the HydroHeal research.

WA

Wafa Shamsan Al-Arjan

Co-author of the HydroHeal research.

Frequently asked questions

What drug does HydroHeal carry?

Silver sulfadiazine, a widely used antibacterial for wounds and burns.

How long does it release the drug?

It released 87.9% of the drug over 48 hours in the lab.

Is it safe for blood contact?

All composite hydrogels tested were hemocompatible.

Who developed it?

Researchers including Rashid Amin.

The research

Peer-reviewed science behind HydroHeal.

Read the full study behind the product.

Read the paper

Khan, M. U. A., Razaq, S. I. A., Mehboob, H., Rehman, S., Al-Arjan, W. S., & Amin, R. (2021). Antibacterial and Hemocompatible pH-Responsive Hydrogel for Skin Wound Healing Application: In Vitro Drug Release. Polymers, 13(21), 3703.

https://doi.org/10.3390/polym13213703